Haemonchus placei

BioProject PRJEB509 | Data Source Wellcome Sanger Institute | Taxonomy ID 6290

About Haemonchus placei

The nematode Haemonchus placei, or large stomach worm, twisted wire worm, is primarily a parasite of ruminants in tropical regions. The disease haemonchosis is characterised by anemia, edema, and weight loss and very heavy infections often cause death in young and well-fed animals.

Genome Assembly & Annotation

Assembly

The draft genome assembly was produced by the Parasite Genomic group at the Wellcome Trust Sanger Institute, in collaboration with John Gilleard (University of Calgary) as part of the 50 Helminth Henomes project. The assembly uses Illumina paired-end sequencing followed by an in-house genome assembly pipeline comprising various steps, including contig assembly, scaffolding, gap-filling and error-correction.

Annotation

The gene predictions were made by the Parasite Genomics group at the Wellcome Trust Sanger Institute and WormBase, as part of the 50 Helminth Genomes Initiative. An in-house pipeline was developed that used MAKER to generate high-quality annotations by integrating evidence from multiple sources: ab initio gene predictions from AUGUSTUS, GeneMark-ES, and SNAP; projected annotation from C. elegans (using GenBlastG) and the taxonomically nearest reference helminth genome (using RATT); and ESTs, mRNAs and proteins from related organisms aligned to the genome using BLAST, with refinement of alignments using Exonerate.

Key Publications

Assembly Statistics

AssemblyH_placei_MHpl1_0011_upd, GCA_900617895.1
StrainMHpl1
Database VersionWBPS18
Genome Size259,125,910
Data SourceWellcome Sanger Institute
Annotation Version2014-06-50HGPpatch

Gene counts

Coding genes21,928
Gene transcripts21,928

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