Brugia timori

BioProject PRJEB4663 | Data Source Wellcome Sanger Institute | Taxonomy ID 42155

About Brugia timori

The nematode Brugia timori is a filarial parasite that infects humans, causing lymphatic filariasis. It is transmitted when infected mosquitoes take a human blood meal. B. timori is found in Indonesia.

Genome Assembly & Annotation

Assembly

The draft genome assembly was produced by the Parasite Genomic group at the Wellcome Trust Sanger Institute, in collaboration with Rick Maizels (Edinburgh University) as part of the 50 Helminth Genomes project. The assembly uses Illumina paired-end sequencing followed by an in-house genome assembly pipeline comprising various steps, including contig assembly, scaffolding, gap-filling and error-correction.

Annotation

The gene predictions were made by the Parasite Genomics group at the Wellcome Trust Sanger Institute and WormBase, as part of the 50 Helminth Genomes project. An in-house pipeline was developed that used MAKER to generate high-quality annotations by integrating evidence from multiple sources: ab initio gene predictions from AUGUSTUS, GeneMark-ES, and SNAP; projected annotation from C. elegans (using GenBlastG) and the taxonomically nearest reference helminth genome (using RATT); and ESTs, mRNAs and proteins from related organisms aligned to the genome using BLAST, with refinement of alignments using Exonerate.

Key Publications

Assembly Statistics

AssemblyB_timori_Indonesia_v1_0_4_001_upd, GCA_900618025.1
StrainFlores island/ Indonesia
Database VersionWBPS18
Genome Size64,930,714
Data SourceWellcome Sanger Institute
Annotation Version2014-06-50HGPpatch

Gene counts

Coding genes16,203
Gene transcripts16,203

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